Backed by 25+ years of research & innovation

From the NAD+ authority trusted by physicians, athletes, researchers, and a Nobel Prize-winning biochemist

  • 45+

    Human Clinical Studies on Niagen@ NR

  • 60+

    Proprietary NR Patents

  • 500+

    Published Scientific Studies

  • 300+

    Global Research Collaborations

    NAD+ keeps you moving

    Your muscle cells are among the most energetically demanding cells in your body. You might remember from high school biology that muscle cells use ATP (adenosine triphosphate) for energy.

    What you might not have learned is that ATP cannot be produced without NAD+ (nicotinamide adenine dinucleotide). Without NAD+, there's no ATP, and without ATP, your muscles cannot function effectively

    The link between muscle health and aging better

    Physical activity, NAD+, and healthy aging are closely interconnected. The phrase "use it or lose it" is quite appropriate here.

    Clinical studies have shown that a sedentary lifestyle over time leads to lower NAD+ levels, which in turn can accelerate the signs of aging. Regular exercise,combined with other healthy lifestyle habits, helps boost NAD+ levels, leading to a slower decline and fewer signs of aging

    For optimal results, complement your exercise routine with Tru Niagen® for additional NAD+ support. While exercise alone can only take you so far, this combined approach helps you stay active as you age and reduces the physical hallmarks of aging.

    Prioritize lifelong movement and mobility with science-backed solutions

    Supporting and maintaining muscle health isn't about looking good in a bathing suit (though that's certainly a beneficial side effect). It's about continually and comprehensively using your muscles in different ways to support graceful movement and strength as you age. The U.S. Department of Health and Human Services' National Institute on Aging outlines four types of exercise-endurance, strength, balance, and flexibility. All have different benefits, and together they help to reduce exercise fatigue and risk of injury.

    MEET OUR STAR SUPERNUTRIENT

    The #1 NAD+ booster3

    Discover Tru Niagen, a revolutionary supplement backed by decades of research and clinically proven to increase NAD+ up to 150% to keep your cells performing at their best.

    Powered by Niagen®, our patented form of nicotinamide riboside, Tru Niagenis one of the most well-researched, efficient, and superior NAD+ precursors available, ensuring you get the best for your health.

    SHOP NOW

    Whole-body benefits

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    • Healthy Aging'

      Boost NAD+ levels for energized resilient cells, ready for repair at any time.

    • Brain

      Power your hardworking brain cells with increased cellular energy.

    • Heart

      Support your heart cells with the essential care they need for cellular resilience.

    • Musclei

      Energize muscle cells to help fuel muscle recovery and repair.

    • Cellular Health

      Support your 37.2 trillion cells with ncreased NAD+ for energy and repair.

    • Lifestyle Stress Management*

      Help counter the impact of physiological stress on your cells that further deplete NAD+

      • I have been using Tru Niagen for a few years now. I find that it gives me an energy boost; have not gotten sick this season either.

        Mary B

      • I'm having a really positive experience with this product; my energy stays very stable throughout the day. I love it.


        Nahomi C

      • It took about 30 days to feel the product working. Been taking tru niagen for 5 years. I'm 66 years old. Do not look or feel my age. Will continue this product forever

        Lisa M.

      • ''It's made all the difference in the world. In every aspect of my health.. I feel better now at 70 than I did at 50.Seriously."


        Kelly C

      • "I have been taking this product for about a year and a half, and I have to say it has given my quality of life a big boost! What a difference it makes for me."

        Jeremiah Thomas

        Frequently Asked Questions

        What is NAD+ and how does it work?

        NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every cell of your body that powers hundreds of metabolic processes. It serves as a key player in cellular energy production, DNA repair, and cellular communication. NAD+ works by transferring electrons during cellular metabolism, enabling your cells to convert nutrients into energy and supporting essential functions that keep your body running optimally.

        What are the potential benefits of taking NAD+ supplements?

        NAD+ levels naturally decline from birth, accelerating around age 30, and dropping by up to 65% by age 70. Environmental and lifestyle stressors also diminish NAD+ levels, as do immune and health challenges. Taking a clinically proven supplement like Tru Niagen helps maintain your NAD+ baseline levels with daily use—to keep your body running smoothly as you age.

        What is the difference between Tru Niagen and other NAD brands on the market?

        Tru Niagen is a superior choice compared to other NAD supplements because it contains Niagen®, our patented nicotinamide riboside (NR), a more bioavailable precursor to NAD+. Niagen® NR is backed by 35+ human clinical studies, and crosses cell membranes easily and is more efficiently converted into NAD+ inside cells, effectively boosting NAD+ levels. 

        This enhances energy metabolism, supports cellular repair, and promotes healthy aging, making Tru Niagen a more reliable, high-quality, pure, and potent option for raising NAD+ compared to other supplements. Tru Niagen® is clinically shown to increase NAD+ levels by over 50% with 300mg daily and by up to 150% with 1000mg daily and is backed by third-party quality-testing from NSF Certified for Sport and Alkemist Labs. 

        How quickly can I expect to see results from taking Tru Niagen?

        Most people report noticing improvements in cellular energy and overall wellbeing within 2-4 weeks of consistent daily use. However, the cellular health benefits of increased NAD+ levels begin immediately, even before you feel noticeable changes.  

        Clinical studies show that Tru Niagen begins elevating NAD+ levels within hours of taking your first dose, with significant increases observed within 2 weeks of daily supplementation. For optimal results, we recommend taking Tru Niagen consistently as part of your daily routine. 

        Is Tru Niagen safe, and are there any side effects?

        Tru Niagen has been rigorously tested for safety and is well-tolerated. Our proprietary key ingredient Niagen® has successfully completed multiple FDA safety reviews and is manufactured in cGMP-certified facilities in the USA.  

        Niagen is supported by 35+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen.² Niagen is also backed by independent research, with over 90% of Niagen studies being investigator-driven and third-party funded. 

        In clinical studies, participants reported minimal to no side effects when taking the recommended dosage up to 2,000mg per day. Some individuals may experience mild and temporary effects that typically resolve quickly. As with any supplement, we recommend consulting with your healthcare provider before starting Tru Niagen, especially if you have existing health conditions or take medications.